Publications by authors named "Annette KeSS"

Trauma causes the breakdown of membrane phospholipids and the subsequent degradation of the released polyunsaturated fatty acids (PUFAs) to partially bioactive oxylipins. Here, we screened for circulating PUFAs and oxylipins in patients (n = 34) differing from those of uninjured controls (n = 25) and analyzed their diagnostic potential. Patients were followed up for 1 to 240 h after minor/moderate, severe, and very severe injuries.

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This prospective, multicenter observational cohort study was carried out in 12 trauma centers in Germany and Switzerland. Its purpose was to evaluate the rate of undertriage, as well as potential consequences, and relate these with different Trauma Team Activation Protocols (TTA-Protocols), as this has not been done before in Germany. : Each trauma center collected the data during a three-month period between December 2019 and February 2021.

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Article Synopsis
  • Trauma triggers an immediate immune response to help clear damaged cells and their associated signaling molecules, known as DAMPs.
  • In severely injured patients, neutrophils showed a consistent pattern of increased EMR2 expression, peaking at 48 hours post-injury, before declining in some cases.
  • The study suggests that the rise in neutrophilic EMR2 is driven by damaged cells and DAMPs, potentially enhancing the body's ability to respond to trauma effectively.
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Objective: Recently several industrialized countries reported a stabilization or even a decrease in childhood overweight and obesity prevalence rates. In Germany, this trend started in 2004. The present study therefore aimed to evaluate whether this trend has continued or even leads in a clear direction.

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