Safety, Efficacy, and Clinical Impact of Penicillin Skin Testing in Immunocompromised Cancer Patients.

Background: Use of penicillin skin testing (PST) to rule out penicillin (PCN) allergies is safe and effective in immunocompetent patients; however, data on immunocompromised patients are limited.

Objective: We aimed to determine safety, efficacy, and clinical impact of PST in immunocompromised patients with cancer.

Methods: A quality improvement process establishing a PST service was implemented at MD Anderson Cancer Center.