Monomorphic agranular natural killer cell lymphoma/leukemia with no Epstein-Barr virus association.

The conceptual view of natural killer (NK) cell malignancies has recently undergone a significant evolution. The majority of such diseases are associated with Epstein-Barr virus (EBV), while only a limited number of EBV-negative cases has been reported. We report an unusual case of NK cell lymphoma/leukemia showing a monomorphic histology, absence of intracytoplasmic azurophilic granules, and no EBV association.

201Tl SPET in the differential diagnosis of brain tumours.

The aims of this study were to assess the utility of 201Tl single photon emission tomography (SPET) in the differential diagnosis of brain tumours and to elucidate the relationship between 201Tl tumour uptake and degree of contrast-enhancement on magnetic resonance imaging (MRI). Early (15 min) and delayed (3 h) 201Tl SPET imaging and T1-weighted MRI were performed before and after Gd-DTPA enhancement in 101 (41 malignant and 60 benign) untreated brain tumours. The 201Tl uptake ratio (tumour-to-normal brain count ratio) for both the early and delayed SPET studies and the retention index (the ratio of delayed to early 201Tl uptake) were calculated.

Cardiac tamponade originating from primary gastric signet ring cell carcinoma.

A 45-year-old man with dry cough and dyspnea was referred by a medical practitioner for evaluation of heart failure on February 10, 1996. Chest X-ray revealed increased cardiothoracic ratio, and ultrasonographic echocardiography disclosed massive pericardial effusion with right ventricular collapse. Cardiac tamponade was diagnosed and pericardiocentesis was performed.

Primary hepatic lymphoma in a patient with chronic hepatitis B.

Primary hepatic lymphoma is a rare disorder and the clinical behavior remains unknown. We report a patient with primary hepatic lymphoma who had chronic hepatitis B. She was asymptomatic; however, a solitary tumor in the left lobe was incidentally detected.

Thyroid nodules: evaluation with US-guided core biopsy with an automated biopsy gun.

To evaluate the efficacy of ultrasound (US)-guided automated core biopsy of thyroid nodules, 74 biopsies were performed in 61 consecutive patients with an 18-gauge short-throw (1.1-cm excursion) biopsy gun. Results were correlated with diagnoses made at surgery (n = 38) or at sonographic follow-up of at least 6 months (n = 36).

[US-guided core biopsy of the breast with an automated biopsy gun: comparison with an aspiration core needle device].

To evaluate the efficacy of an automated Tru-cut type of biopsy gun in US-guided breast biopsy, we performed 162 breast biopsies in 148 patients using an 18 gauge short-throw (1.1cm excursion) Tru-cut-type biopsy gun (Ace-cut needle). The results of the series were compared with another series of aspiration core biopsies, which were performed on 113 breast lesions in 112 patients using an 18 gauge Sure-cut needle.

Tsukuba high- and low-emotional strains of rats (Rattus norvegicus): an overview.

This report compiles the results of a series of studies on the Tsukuba High- and Low-Emotional strains (THE and TLE) of rats (Rattus norvegicus) established at the University of Tsukuba, Japan. The THE and TLE strains have been selected, respectively, for low and high activity in a runway test. During the course of selection, defecation has increased in the THE strain and decreased in the TLE strain.

Studies on the autonomic nervous function in Tsukuba emotional rats--with special reference to their cardiac function.

Autonomic nervous function in Tsukuba high (THE) and low (TLE) emotional rats as well as Wistar rats (control) was studied by means of electrocardiographical examination in addition to the runway test. In the runway test, locomotive activity differed significantly among the three strains, the greatest activity in TLE and the smallest in THE. Electrocardiogram (ECG) and locomotive activity were successively recorded for 24 hr using a small size of telemeter system.

Mucin-producing poorly differentiated adenocarcinoma of the thyroid. A case report.

A rare case of mucin-producing poorly differentiated adenocarcinoma of the thyroid is reported in a 58-year-old man. Light microscopically, the tumor composed of columnar cells, cuboidal cells and spindle cells and these tumor cells showed a various growth pattern; glandular growth with columnar cells, microfollicular growth with cuboidal cells and solid growth with spindle cells. Mucin histochemistry showed scattered foci of mucin production.

[A case of metastatic hepatocellular carcinoma of the superior mediastinum].

A 58-year-old man, who had undergone right hepatic lobectomy for hepatocellular carcinoma 6 years before, complained of hoarseness because of right recurrent laryngeal nerve paralysis. Chest X-ray film showed a large mass shadow in the superior mediastinum. On chest CT scan the mass was considered to be swollen paratracheal lymph nodes.

[A case of subclavian paraganglioma in the superior mediastinum extending to the neck].

A 52-year-old female was admitted to our hospital with left anterior chest pain. On physical examination, an elastic hard mass sized in 3.0 x 2.

[A case of dumb-bell-like neurilemmoma of the posterior mediastinum].

A 56 year-old female was pointed out an abnormal shadow on chest X-ray film for the lung cancer screening study. Chest X-ray film showed a round mass shadow at the right superior mediastinum. Chest CT scan revealed the mass was in the paravertebral area abutting on the 2nd thoracic vertebral body and had extended into the intervertebral foramen.

[The sequential structures of social behavior and their developmental changes in rats bidirectionally selected for emotionality].

Eighteen colonies of Tsukuba High Emotional (THE) and 17 colonies of Low Emotional (TLE), each one composing of one female and two male rats, were reared for about two months. During this period, intruder tests and intra-colony observations were conducted once a week. Social behavior of colony residents was coded sequentially with 17 items in a microcomputer.

[Combined treatment of irradiation and 8 MHz radiofrequency hyperthermia with chemoembolization in advanced renal tumor].

A combined treatment of irradiation and 8 MHz radiofrequency hyperthermia after chemoembolization, using 20 mg of microencapsulated mitomycin C (MMC.mc), was undertaken in a patient with an advanced left renal tumor. The patient, a 70-year-old man, noticed a gross hematuria in February, 1984.

Septal lesions and biting attacks in rats bidirectionally selected for emotionality.

Twenty-nine colonies composed of one female and two male rats of high or low emotional strain were established. A dominant male of each colony was identified based on its attacks on an intruder rat. It was found that dominant males of the low emotional strain colonies were significantly more aggressive than those of the high emotional strain.