Publications by authors named "Annemarie Amtoft"

We present the F-Fluorodeoxyglucose (F-FDG) positron emission tomography/computed tomography (PET/CT) findings in a 57-year-old woman with post-menopausal bleeding diagnosed with hepatoid adenocarcinoma (HAC) with a primary tumour in the uterine corpus and a highly elevated level of serum-α-fetoprotein (S-AFP) at presentation. HAC is a variant of adenocarcinoma with hepatic differentiation representing a heterogeneous group of neoplasms that morphologically and immunphenotypically resemble hepatocellular carcinoma (HCC) but are of extrahepatic origin. Microscopically, they are usually poorly differentiated adenocarcinomas proliferating in solid sheets or in a trabecular or cord-like arrangement.

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Radiation-induced changes may cause a non-malignant high 2-deoxy-2-[F]fluoro-d-glucose (FDG)-uptake. The 3'-deoxy-3'-[F]fluorothymidine (FLT)-PET/CT performs better in the differential diagnosis of inflammatory changes and lung lesions with a higher specificity than FDG-PET/CT. We investigated the association between post-radiotherapy FDG-PET-parameters, FLT-PET-parameters, and outcome.

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Diagnosing relapse after radiotherapy for lung cancer is challenging. The specificity of both CT and F-FDG PET/CT is low because of radiation-induced changes. 3'-deoxy-3'-F-fluorothymidine (F-FLT) PET has previously demonstrated higher specificity for malignancy than F-FDG PET.

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In illicit drug use, "skin popping" refers to the method of administering drugs by injecting it into the subcutaneous tissue. "Skin popping" can lead to acute and chronic skin manifestations caused by the drug itself and/or by the various adulterants and fillers commonly added to drug substances. Chronic skin manifestations include a foreign-body reaction with formation of granulomas at the site of injection.

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We present the PET/CT findings of extensive disseminated genital herpes simplex virus infection in a 29-year-old woman known with disseminated anaplastic lymphoma kinase-mutated nonsmall lung cancer. PET/CT revealed extensive involvement of the outer and inner genitalia, multiple lymph nodes extending from the porta hepatis to the groins, and involvement of the liver. Disseminated herpes simplex virus infection is well described in neonates and immunocompromised individuals but very rare in immunocompetent adults as was the case with this patient.

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Graft-versus-host-disease (GVHD) following stem cell transplantation (SCT) is a common complication in patients that have undergone allogenic SCT but rare in recipients of autologous SCT. Gastro-intestinal tract (GIT)-GVHD can be difficult to diagnose due to non-specific symptoms such as fever, nausea, diarrhea, and vomiting; a histological confirmation is therefore required. Here, we present the findings of a whole-body FDG PET/CT with extensive and multifocal involvement of the GIT in a patient that developed severe acute GVHD 93 days post autologous SCT for Hodgkin's lymphoma.

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Tracheomalacia is a rare condition involving increased flaccidity of the tracheal cartilage, widening of the posterior membranous wall and a reduced airway calibre. This combination can cause a tracheal collapse, expiratory flow obstruction and decreased clearance of secretions. We present a case of a 70-year-old woman with severe coughing symptoms and obvious tracheomalacia diagnosed with a high resolution computed tomography in the expiratory phase.

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