Publications by authors named "Annemarie A van Drimmelen"
Phenotypic patient profiling for improved implementation of guideline-directed medical therapy: An exploratory analysis in a large real-world chronic heart failure cohort.
Sumant P Radhoe Pascal R D Clephas Gerard C M Linssen Remko M Oortman Frank J Smeele Annemarie A Van Drimmelen
Front Pharmacol
March 2023
Article Synopsis
- Researchers found it tough to give heart failure patients the best medications, even though there are guidelines.
- In 2021, a group called the European Heart Failure Association created patient profiles based on their health traits to help tailor treatments better.
- They studied 4,455 heart failure patients and discovered that almost 40% could fit into these profiles, which could lead to better and more personalized treatments.
Objectives: This study investigated adherence to drug therapy guidelines in heart failure (HF) with reduced left-ventricular ejection fraction (LVEF) of <40% (heart failure with reduced ejection fraction [HFrEF]), in which evidence-based treatment has been established.
Background: Despite previous surveys of HF, important uncertainties remain regarding guideline adherence in a representative real-world population.
Methods: A cross-sectional registry in 34 Dutch HF outpatient clinics that included 10,910 patients with the diagnosis of HF was examined.