Interaction of flavan-3-ol derivatives and different caseins is determined by more than proline content and number of proline repeats.

Interactions of Type A and B flavan-3-ol dimers (procyanidins) and several monomeric flavan-3-ols, with α-casein and β-casein, were investigated. Binding affinities measured were related to the ligands structure, including several properties (e.g.