Clinical decision-making in older patients with cancer: a cross-sectional single-centre study to assess the impact of clinical judgement and patient preferences.

Objective: The heterogeneity in the population of older patients with cancer makes clinical decision-making difficult. We investigated the agreement between the G8 score and clinical judgment in frailty assessments, determined the impact of a life-expectancy calculator, and explored patient and caregiver preferences towards the treatment goal.

Methods: Patients aged ≥75 years in need of new oncological treatment were prospectively enrolled between June 2020 and February 2021.

Paraneoplastic Cushing syndrome, case-series and review of the literature.

Objectives: Paraneoplastic Cushing syndrome is a rare condition, representing a small fraction of the adrenocorticotropic hormone (ACTH)-dependent cases of Cushing syndrome Methods: Four case descriptions and literature review, highlighting the diagnostic challenges and treatment options are presented.

Results: Different tumor types can be associated with ectopic ACTH secretion. The most common types are bronchial carcinoids and small cell lung carcinoma (SCLC).

Functional outcome after Ivor Lewis esophagectomy for cancer.

Background: Little is known on functional outcome after Ivor Lewis esophagectomy (ILE) with intrathoracic anastomosis.

Methods: Patients who underwent ILE were identified from a prospective database. Clinicopathological data were retrieved and compared with functional outcome data based on patient self-assessment by a standard questionnaire.