Publications by authors named "Anne-Sophie van Schelt"
Article Synopsis
- The study focused on improving dynamic contrast-enhanced (DCE) MRI by optimizing pseudo-spiral (PS) k-space sampling patterns, which are crucial for obtaining high-quality images while minimizing undersampling issues.* -
- Researchers simulated contrast agent inflow in different abdominal organs and evaluated 704 sampling and reconstruction methods based on image quality and pharmacokinetic parameter accuracy, eventually identifying a superior PS sampling strategy.* -
- The best strategy, which uses a specific distribution of readouts and regularization techniques, resulted in sharper images with fewer artifacts in healthy participants and showed promising results in a patient with pancreatic ductal adenocarcinoma (PDAC).*
Background: Magnetic resonance elastography (MRE) is a non-invasive method to measure the viscoelastic properties of tissue and has been applied in multiple abdominal organs. However, abdominal MRE suffers from detrimental breathing motion causing misalignment of structures between repeated acquisitions for different MRE dimensions (e.g.
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- This study explores the use of magnetic resonance elastography (MRE) as a method to quantify fibrosis in the mesentery for patients with Crohn's disease (CD), addressing the limitations of conventional imaging.
- Results indicated that MRE could effectively differentiate between fibrotic and healthy mesenteric tissue, showing significant differences in stiffness and fluidity between CD patients and healthy individuals.
- The findings suggest that MRE may be a valuable tool for guiding surgical decisions, like whether to perform extended mesenteric resection, based on the extent of disease involvement in the mesentery.
Background: Pancreatic ductal adenocarcinoma (PDAC) stromal viscoelasticity can be measured using MR elastography (MRE). Bowel preparation regimens could affect MRE quality and knowledge on repeatability is crucial for clinical implementation.
Purpose: To assess effects of four bowel preparation regimens on MRE quality and to evaluate repeatability and differentiate patients from healthy controls.
Article Synopsis
- The study investigates a new noninvasive MR elastography (MRE) technique called compressed sensing MRE (CS-MRE) aimed at accurately assessing pancreatic stiffness related to pancreatic ductal adenocarcinoma (PDAC) without position errors.
- It involved 30 healthy volunteers and 5 patients with PDAC, optimizing an existing four-breath-hold MRE method and comparing it with the new CS-MRE method.
- Results showed that CS-MRE provided similar quantitative measures of stiffness compared to the traditional method, demonstrating significant differences in shear wave speed between healthy subjects and PDAC patients.