Publications by authors named "Anne-Sophie Lecompte"
Article Synopsis
- The ANRS|MIE CoviCompareP study investigated COVID-19 breakthrough infections among vaccinated adults during the Omicron variant's circulation, focusing on those vaccinated with the Pfizer-BioNTech vaccine.
- The study involved healthy adults divided into groups based on previous SARS-CoV-2 infection status and monitored their neutralizing antibodies after vaccination and boosters.
- Results showed that 31% of participants experienced breakthrough infections, with lower infection risks linked to older age, more booster doses, and higher neutralizing antibody levels, especially in those with prior infections.
Immune response induced by COVID-19 vaccine booster against delta and omicron variants was assessed in 65 adults (65-84 years old) early aftesr a first booster dose. An increase in SARS-CoV-2 neutralizing antibodies was shown in individuals not previously infected without evidence of an age-related effect, with lower increase in those infected before a single dose of primary vaccination. Of note, humoral response was observed only starting from the 5th day after the boost.
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