Publications by authors named "Anne-Sophie Barret"
BackgroundIn 2022, a global monkeypox virus (MPXV) clade II epidemic occurred mainly among men who have sex with men. Until early 1980s, European smallpox vaccination programmes were part of worldwide smallpox eradication efforts. Having received smallpox vaccine > 20 years ago may provide some cross-protection against MPXV.
View Article and Find Full Text PDFHuman Papillomavirus (HPV) vaccine coverage was <50% in France in 2022 and even lower among socially disadvantaged populations. We aimed to evaluate socio-demographic determinants of HPV vaccine awareness, uptake, and intention among parents of adolescents, and related attitudes and knowledge items. Parents of adolescents attending middle schools across France, who participated in a randomized trial responded to an anonymous baseline survey, conducted between November 2021 and February 2022.
View Article and Find Full Text PDFArticle Synopsis
- Invasive meningococcal disease (IMD) is a serious illness caused by the bacterium Neisseria meningitidis, often leading to meningitis or septicemia.
- There are six main serogroups (A, B, C, W, X, Y) responsible for the majority of cases, which can spread through respiratory droplets and secretions from infected individuals or carriers.
- Vaccination is available to prevent IMD, and giving antibiotics to close contacts of infected people is vital to stop further infections.
Background: With the aim to optimize communication during HPV vaccination campaigns in France, we elicited parental preferences around HPV vaccination.
Methods: We conducted a single-profile discrete choice experiment (DCE) among parents of 11- to 14-year-old middle-school pupils, who completed an anonymous, self-administered, internet-based questionnaire during 2020-2021. The DCE comprised five attributes (vaccine-preventable disease, justification of optimal age, information on safety, indirect protection and coverage) of vaccination against an unnamed disease that were presented to respondents in ten choice tasks, or scenarios.
Objectives: The aim was to estimate the effect of reported history of smallpox vaccination prior to 1980 on clinical expression of mpox.
Methods: We included all confirmed mpox cases identified by the national mpox surveillance system in France between May and July 2022. Cases tested positive for monkeypox virus or orthopoxviruses by PCR.
BackgroundIn France, human papillomavirus (HPV) vaccination coverage varies across socioeconomic levels.AimWe aimed at assessing HPV vaccine awareness, uptake and vaccination intention among adolescents in France.MethodsIn a cluster-randomised study, 13-15-year-old students in 61 French middle schools completed a web-based questionnaire.
View Article and Find Full Text PDFMen who have sex with men (MSM) are at high risk of sexually transmitted infections, among which HPV infections are particularly prominent. We took advantage of the MémoDépistages study to evaluate HPV distribution at anal and oropharyngeal sites in HIV-negative multipartner MSM. HPV DNA was detected in 82% (n = 344) of anal and 11% (n = 45) of oropharyngeal self-collected samples taken from 421 participants.
View Article and Find Full Text PDFArticle Synopsis
- In France, HPV vaccination is recommended for men who have sex with men (MSM) up to age 26, but a 2019 survey found only 15% of MSM aged 18-28 reported receiving the vaccine.
- Higher vaccine uptake was associated with younger MSM, lower education levels, living in rural areas, attending sex parties, using HIV prevention methods, and having a history of STIs or receiving other vaccinations like Hepatitis A or B.
- The study concludes that while HPV vaccination rates are low among MSM in France, those already engaged in other preventive health measures have higher rates, indicating the need for improved outreach and education on HPV vaccination.
Article Synopsis
- In December 2016, a series of serogroup B invasive meningococcal disease cases were reported among middle and high school students in Côtes-d'Armor, France, prompting a vaccination campaign using the Bexsero® vaccine.
- The campaign targeted approximately 8,884 individuals, with on-site vaccinations organized in schools and additional vaccinations provided by local general practitioners in the community between May and October 2017.
- Despite varying coverage rates (43% for one dose and 34% for two doses), higher vaccination rates were seen in schools compared to the community, and there were no reports of severe adverse effects, indicating the campaign's effectiveness.
Article Synopsis
- The study examines the changing landscape of invasive meningococcal disease (IMD) in France, particularly focusing on the recent emergence of a new genotype, ST-9316, distinct from the previously dominant clonal complex ST-11 (CC11).
- Researchers used epidemiological data and whole genome sequencing to analyze these strains and their relationship to vaccine-induced immunity, as well as their virulence in transgenic mice.
- Findings indicate that ST-9316 primarily affects infants under one year old and shows lower virulence compared to ST-11, highlighting the need for enhanced surveillance of emerging strains.
In France, every year, HPVs cause approximately 6,300 cancers -cervix, anus, oropharynx, penis, vulva, vagina, oral cavity, larynx- representing 2% of all incident cancers, 35,000 precancerous le-sions of the cervix, and at least 50,000 condylomas in the under- 30s. All 3,000 new cases of cervical cancers are attributable to HPV infections. Cervical cancer prevention is based on the combination of two complementary strategies: vaccination of 11 to 14-years-old girls against HPV and organized screening of cervical cancer for women between 25 and 65 years old.
View Article and Find Full Text PDFOne year after the extension of the childhood vaccination mandates to the 11 routine vaccinations for children under 2 years old, we estimated vaccination coverage through vaccine reimbursement data. Coverage for children born in 2018 has notably increased. Moreover, vaccine coverage for children and for vaccines not concerned by the law have also shown an increasing trend, supporting a positive impact of the ongoing communication strategy on vaccination, beyond the extension of vaccination mandates.
View Article and Find Full Text PDFBackground: Neisseria meningitidis group W (NmW) belonging to the clonal complex ST-11 (NmW/cc11) spread in Europe and in France in 2000 and declined thereafter. In France, invasive meningococcal disease (IMD) due to NmW increased again in 2012 and thereafter since 2015. Several sub-lineages of NmW/cc11 are circulating worldwide with successive epidemic waves.
View Article and Find Full Text PDFBetween February and May 2017, two cases of invasive meningococcal disease caused by a new, rapidly expanding serogroup W meningococci variant were reported among students of an international university in Paris. Bacteriological investigations showed that isolates shared identical genotypic formula (W:P1.5,2:F1-1:cc11) and belonged to the South American/UK lineage.
View Article and Find Full Text PDFBackground: In the third season of I-MOVE (Influenza Monitoring Vaccine Effectiveness in Europe), we undertook a multicentre case-control study based on sentinel practitioner surveillance networks in eight European Union (EU) member states to estimate 2010/11 influenza vaccine effectiveness (VE) against medically-attended influenza-like illness (ILI) laboratory-confirmed as influenza.
Methods: Using systematic sampling, practitioners swabbed ILI/ARI patients within seven days of symptom onset. We compared influenza-positive to influenza laboratory-negative patients among those meeting the EU ILI case definition.
Background: A multicentre case-control study based on sentinel practitioner surveillance networks from seven European countries was undertaken to estimate the effectiveness of 2009-2010 pandemic and seasonal influenza vaccines against medically attended influenza-like illness (ILI) laboratory-confirmed as pandemic influenza A (H1N1) (pH1N1).
Methods And Findings: Sentinel practitioners swabbed ILI patients using systematic sampling. We included in the study patients meeting the European ILI case definition with onset of symptoms >14 days after the start of national pandemic vaccination campaigns.