Publications by authors named "Anne-Marie de la Bigne"
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Synopsis of recent research by authors named "Anne-Marie de la Bigne"
- Recent research by Anne-Marie de la Bigne focuses on the pharmacological evaluation of S81694, a monopolar spindle 1 kinase inhibitor, specifically in the context of advanced, metastatic solid tumors.
- The first-in-human Phase I study aimed to establish a safe dosing schedule, evaluate the drug's safety and tolerability, and identify any dose-limiting toxicities in adult patients.
- Findings from the study provide critical insights into the maximum tolerated dose (MTD) and recommended phase II dose (RP2D) for S81694, enhancing the understanding of its therapeutic potential in oncology.