- The ADRISK trial is a study focused on patients with locally advanced head and neck squamous cell carcinoma (HNSCC) who are at high risk of recurrence after surgery.
- It compares the effectiveness of standard adjuvant radio(chemo)therapy (aRCT) with cisplatin to aRCT combined with pembrolizumab, an immunotherapy drug, in improving event-free survival.
- The trial involves 240 patients with specific criteria and aims to assess outcomes in terms of event-free and overall survival, with recruitment commencing in August 2018 and still ongoing.