No negative impact of reduced leptin secretion on bone metabolism in male decathletes.

This study investigated the effect of intense physical activities that generate high mechanical constraints on bone metabolism and serum leptin concentrations and the potential relationships among bone mineral density (BMD), bone biochemical markers and leptin variation. Thirteen male decathletes (mean age 22.4 +/- 2.

Circulating leptin concentrations can be used as a surrogate marker of fat mass in acute spinal cord injury patients.

To determine the acute effect of neurological lesion on body composition, plasma leptin level, and the lipid profile, 7 male patients with acute and complete spinal cord injury (SCI) and 9 able-bodied (AB) males were investigated. At 16, 24, 36, and 48 weeks after injury, plasma leptin level and the lipid profile were analyzed, while whole body (WB) and regional fat mass (FM) and fat-free soft tissue (FFST) were measured by dual-energy x-ray absorptiometry (DXA). At all stages, despite no difference being found between both groups for body mass index (BMI), SCI patients had higher FM at WB (P < .