The Locus in Anginosus Group: Interspecies Competition and a Hotspot of Genetic Diversity.

The Invasion Locus () was first described in and , where it has been implicated in virulence. The two-component peptide signaling system consists of the SilA response regulator and SilB histidine kinase along with the SilCR signaling peptide and SilD/E export/processing proteins. The presence of an associated bacteriocin region suggests this system may play a role in competitive interactions with other microbes.