Intravascular metastatic melanoma of the vena saphena magna.

Background: Melanoma blood vessel metastases are very uncommon. We report the first recorded case of intravascular metastatic melanoma of the vena saphena magna.

Case Report: A 74-year-old woman presented with a swelling of the upper third of her left thigh and was suspected of superficial thrombophlebitis.

Increase in total blood antioxidant status and selenium levels in black patients with active vitiligo.

Background: Oxidative stress could be an important phenomenon leading to melanocyte death in vitiligo. The accumulation of hydrogen peroxide (H2O2) and low catalase levels have recently been demonstrated in the epidermis of vitiligo patients. Few abnormalities of antioxidants have been found in the blood of patients with vitiligo, except for an elevation of selenium.

Onychomycosis due to Exophiala jeanselmei.

Background: Exophiala jeanselmei is a dematiaceous fungus that may cause invasive diseases, particularly among immunocompromised hosts. Most reports mention cutaneous or subcutaneous lesions, but no case of nail involvement due to this fungus has been reported until now.

Case Report: A 60-year-old man presented with hyperkeratosis and black coloration of the nails of the two thumbs and the two big toes of 4 years' duration.