Publications by authors named "Anne-Charlotte Dillies"
Article Synopsis
- - Acquired hemophagocytic lymphohistiocytosis (HLH) is a serious condition caused by an overactive immune response, often linked to infections, cancers, autoimmune diseases, and recently, immune checkpoint inhibitors (ICIs) used in cancer treatment.
- - A study analyzed 190 HLH cases related to ICI therapy, finding that most patients were older men, with HLH typically appearing about 102 days post-treatment initiation, particularly with medications like nivolumab and pembrolizumab.
- - Results showed HLH occurrences were significantly higher with ICIs compared to other drugs, leading to serious conditions in patients, with a 15.3% mortality rate, highlighting the need for clinicians to be vigilant for
