Publications by authors named "Anne-Cecile Guillope"
Biomedicines
November 2022
Article Synopsis
- Macrophages are crucial for wound healing and reactions to foreign materials, particularly in the context of the Masquelet technique used for reconstructing limb injuries.
- In a study using rats, metakaolin was tested as an alternative to the standard material PMMA, revealing that the metakaolin-based membranes had enhanced osteogenic factors like TGF-β and BMP-2, promoting better bone healing.
- The research suggests that the immune environment created by macrophages significantly affects the ability of these membranes to support bone regeneration, with metakaolin-induced membranes showing improved characteristics over those made with PMMA.
