In this work, we present a tandem ion mobility spectrometer (IMS) utilizing a highly efficient ion manipulator allowing to store, manipulate, and analyze ions under high electric field strengths and controlled ion-neutral reactions at ambient conditions. The arrangement of tandem drift regions and an ion manipulator in a single drift tube allows a sequence of mobility selection of precursor ions, followed by storage and analysis, mobility separation, and detection of the resulting product ions. In this article, we present a journey exploring the capabilities of the present instrument by a study of eight different primary alcohols characterized at reduced electric field strengths / of up to 120 Td with a water vapor concentration ranging from 40 to 540 ppb.
View Article and Find Full Text PDFDialysis-induced changes in plasma sodium concentration may cause undesirable side effects. To prevent these, the sodium content in dialysis fluid has to be individualized based on the patient's plasma sodium concentration. In this paper, we describe a simple conductivity based method for measuring the plasma sodium concentration.
View Article and Find Full Text PDFCertain applications require a contactless measurement to eliminate the risk of sensor-induced sample contamination. Examples can be found in chemical process control, biotechnology or medical technology. For instance, in critically ill patients requiring renal replacement therapy, continuous in-line monitoring of blood conductivity as a measure for sodium should be considered.
View Article and Find Full Text PDFThe electrical and dielectric properties of liquids can be used for sensing. Specific applications, e.g.
View Article and Find Full Text PDF