Cortical tension promotes Kibra degradation via Par-1.

The Hippo pathway is an evolutionarily conserved regulator of tissue growth. Multiple Hippo signaling components are regulated via proteolytic degradation. However, how these degradation mechanisms are themselves modulated remains unexplored.

Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-mediated transcription.

The Hippo (Hpo) pathway regulates tissue growth in many animals. Multiple upstream components promote Hpo pathway activity, but the organization of these different inputs, the degree of crosstalk between them, and whether they are regulated in a distinct manner is not well understood. Kibra (Kib) activates the Hpo pathway by recruiting the core Hpo kinase cassette to the apical cortex.

Amplified fragment length polymorphism analysis supports the valid separate species status of and (Diptera: Calliphoridae).

Common DNA-based species determination methods fail to distinguish some blow flies in the forensically and medically important genus Robineau-Desvoidy. This is a practical problem, and it has also been interpreted as casting doubt on the validity of some morphologically defined species. An example is and , which co-occur in Europe whilst only has been collected in North America.