Publications by authors named "Anne Trommelholt Holm"
Article Synopsis
- Significant changes in lung capacity and compliance were observed in Mfap4(-/-) mice at 6 and 8 months, along with increased low-attenuation areas indicating potential emphysema-like changes.
- Despite no apparent difference in elastic fiber organization or elastin content, Mfap4(-/-) mice exhibited a decline in lung function and reduced alveolar surface area, emphasizing potential roles in lung elastogenesis and function.
Localization of microfibrillar-associated protein 4 (MFAP4) in human tissues: clinical evaluation of serum MFAP4 and its association with various cardiovascular conditions.
Helle Wulf-Johansson Sofie Lock Johansson Anders Schlosser Anne Trommelholt Holm Lars Melholt Rasmussen Henrik Munkholm Uffe Holmskov
PLoS One
October 2014
Microfibrillar-associated protein 4 (MFAP4) is located in the extracellular matrix (ECM). We sought to identify tissues with high levels of MFAP4 mRNA and MFAP4 protein expression. Moreover, we aimed to evaluate the significance of MFAP4 as a marker of cardiovascular disease (CVD) and to correlate MFAP4 with other known ECM markers, such as fibulin-1, osteoprotegerin (OPG), and osteopontin (OPN).
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