Short-term responses of meat ewes facing an acute nutritional challenge in early-mid lactation.

Simulating a consequence of a climate change event on feed availability, responses of Mediterranean meat ewes facing an acute undernutritional challenge (; i.e., fed only low nutritional value cereal straw) were evaluated at a sensitive physiological stage (i.

Short-, Medium- and Long-Term Metabolic Responses of Adult Meat Ewes Subjected to Nutritional and β-Adrenergic Challenges.

Shortage and refeeding situations lead to switches in metabolic pathways induced by undernutrition and body energy reserve (BR) replenishment cycles. In a 122-d experiment, 36 adult ewes were chosen and first accustomed to diet ingredients (i.e.

GammaH2AX, an accurate marker that analyzes UV genotoxic effects on human keratinocytes and on human skin.

The phosphorylated form of histone H2AX, gammaH2AX, is a component of the DNA repair system. Most studies have focused on the role of gammaH2AX during cell transformation and human cancer, but little is known about its role in keratinocytes and the skin during UV irradiation. We analyzed the response to UV irradiation focusing on the phosphorylation of histone H2AX both in vitro, in keratinocyte cultures and in artificial epidermis, and then in vivo, in human skin.