[A woman in her forties who used addictive drugs in very high doses].

Background: Following a surgical procedure, a female patient in her forties was prescribed opioids (oxycodone). The prescription escalated into doses that were extremely high, and at a level beyond any experienced previously, either at the various hospital units that were involved in the treatment or in the medical literature.

Case Presentation: The patient had no known history of substance abuse.

[Use of drugs for alcohol use disorder in Norway 2004–16].

Background: Alcohol use disorder can lead to serious illness and early death. The lifetime prevalence rate among the Norwegian population is estimated at 7-10 %. Many patients are never admitted to any kind of treatment programme, and it is assumed that few of those who are treated receive medicinal treatment.

Repeated acetylcholine receptor antibody-concentrations and association to clinical myasthenia gravis development.

Introduction: We aimed to examine the longitudinal association between Myasthenia Gravis (MG) clinical severity and concentration of acetylcholine receptor (AChR)-antibodies to evaluate if AChR-antibody variations correlate to disease severity. A positive AChR-antibody test is specific for MG.

Material And Methods: All patients from western Norway who had two or more AChR- antibody tests in the period 1983-2013 were identified.

Geographical distribution of a seropositive myasthenia gravis population.

Introduction: To assess age- and sex-specific myasthenia gravis (MG) occurrence and incidence in the different geographical regions in Norway and thereby to identify factors that may contribute to the development of MG.

Methods: Multiple Poisson regression analysis was used to assess variation in incidence dependent on year, gender and onset age in five geographically defined health regions.

Results: The study population comprised 419 individuals with first time seropositive tests from 1995 to 2007.