Publications by authors named "Anne Sophie Cognee"

The presence of serum monoclonal IgM is often associated with the diagnosis of Waldenström macroglobulinemia (WM) or other chronic lymphoproliferative disorders. IgM myeloma is a rare entity (0.5%).

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IgE myeloma is an extremely rare disease characterized by frequent plasma cell leukemia, little monoclonal-spike on electrophoresis, an high incidence of t(11;14) translocation and a worse survival than those with common myelomas. We report here a new case of IgE myeloma and discuss clinical presentation, biological features and therapeutic option.

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Article Synopsis
  • The study aimed to evaluate the performance of seven French labs in detecting 16S rRNA genes via real-time PCR for diagnosing bone and joint infections (BJIs) within a multicenter research framework.
  • To ensure consistency amidst varying extraction methods and equipment, external quality controls were implemented, including standardized extraction volumes and primer usage.
  • Out of 168 quality controls sent, 93.8% achieved expected results, indicating that both manual and automated extraction methods yielded similar performance, validating the use of molecular diagnostics for BJIs in multicenter studies.
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Invasive candidiasis remains a major cause of morbidity and mortality. It is now well known that an early diagnosis contributes to the patients' outcome. Blood cultures, which are the first-line test in case of bloodstream infection suspicion, can be carried out using fungus-selective medium (containing antibiotics) or standard microorganism medium allowing both bacterial and fungal growth.

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