Publications by authors named "Anne S Hale"
Article Synopsis
- The study aimed to assess the safety and effects of a canine-specific albumin (CSA) product administered repeatedly to healthy Beagles, focusing on any adverse reactions and changes in serum albumin concentrations and colloid osmotic pressure (COP).
- Six healthy adult Beagles were given 1 g/kg of CSA via intravenous infusion on three different days, with monitoring for any negative side effects and measuring serum albumin and COP before and after each infusion.
- Results showed minimal adverse effects (one instance of vomiting) and significant increases in serum albumin and COP levels after each infusion, indicating that the CSA product is safe and effective for enhancing these blood parameters in dogs.
Article Synopsis
- Management of immune thrombocytopenia (ITP) in dogs and cats lacks established evidence-based guidelines, leaving treatment decisions largely to clinician discretion.
- The first-line treatment involves immunosuppressive glucocorticoids, with additional therapies such as azathioprine and vincristine used in more severe cases; however, optimal regimens are still unclear.
- A consensus process involving a structured literature review and expert opinions led to the creation of guidelines highlighting the need for further research in ITP treatment options.
Objective: To describe the periprocedural use of a lyophilized platelet product during rhinoscopic diagnosis and treatment of sinonasal aspergillosis in a Greater Swiss Mountain Dog with a P2Y12 platelet receptor disorder.
Case Summary: After the development of severe epistaxis, a Greater Swiss Mountain Dog was diagnosed with thrombopathia secondary to a P2Y12 receptor gene mutation. Concurrent primary nasal disease was also suspected due to persistent mucopurulent nasal discharge.
Background: Thrombocytopenia in dogs is common in critical care medicine, but availability of fresh platelet concentrates in veterinary medicine can be limiting. Lyophilized platelets have long shelf-lives and can be easily transported, stored, and administered in various settings.
Objective: To evaluate the efficacy and safety of a novel trehalose-stabilized canine lyophilized platelet product in thrombocytopenic dogs with clinically-evident bleeding.
Comparative stability of canine and feline hemostatic proteins in freeze-thaw-cycled fresh frozen plasma.
J Vet Emerg Crit Care (San Antonio)
October 2010
Objective: To evaluate the stability of canine and feline hemostatic proteins in freeze-thaw-cycled (FTC) fresh frozen plasma (FFP).
Design: Prospective study.
Setting: Veterinary Teaching Hospital.
Background: Testing for canine blood types other than dog erythrocyte antigen 1.1 (DEA 1.1) is controversial and complicated by reagent availability and methodology.
View Article and Find Full Text PDFObjective: To determine whether blood type, breed, or sex were risk factors for immune-mediated hemolytic anemia (IMHA) in dogs and whether bacteremia was common in dogs with IMHA.
Design: Case-control study.
Animals: 33 dogs with IMHA, 1,014 dogs without IMHA for which blood type (dog erythrocyte antigens 1.