C3a levels and occurrence of subdermal vascular thrombosis are age-related in deep second-degree burn wounds.

Background: After second-degree burns, thrombosis of the subdermal vascular plexus may occur, necessitating epifascial necrectomy instead of tangential excision to ensure split skin graft healing. Until now, no parameter has been obtained to explain this phenomenon.

Methods: Thirty-four patients with deep second-degree burn wounds were divided into 2 groups.