Publications by authors named "Anne Ninnemann"
Opioid addiction presents a relevant health challenge, with chronic heroin use linked to detrimental effects on various aspects of physical, mental, and sociological health. Opioid maintenance therapy (OMT), particularly using methadone, is the primary treatment option for heroin addiction. Previous studies using blood samples from current heroin addicts and OMT patients have shown immunomodulatory effects of heroin and methadone on T cell function.
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- * Infected mice showed increased levels of Nrp-1+CD8+ T cells, which were linked to neurological issues in ECM and liver damage during LCMV infection, indicating a strong activation state of these T cells.
- * Removing Nrp-1 from T cells led to fewer activated T cells in various organs and reduced disease severity, highlighting Nrp-1's role in worsening T cell responses during