Publications by authors named "Anne M Portaankorva"

Background And Objectives: Data on care home admission and survival rates of patients with syndromes associated with frontotemporal lobar degeneration (FTLD) are limited. However, their estimation is essential to plan trials and assess the efficacy of intervention. Population-based registers provide unique samples for this estimate.

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Background And Objectives: Large-scale genome-wide studies of chronic hydrocephalus have been lacking. We conducted a genome-wide association study (GWAS) in normal pressure hydrocephalus (NPH).

Methods: We used a case-control study design implementing FinnGen data containing 473,691 Finns with genotypes and nationwide health records.

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Article Synopsis
  • - The study examines the incidence and prevalence of early-onset dementia (EOD) in two areas of Finland from 2010 to 2021, finding that the crude incidence rate was 12.3 cases per 100,000 persons per year with specific age groups showing higher rates.
  • - Out of the 794 new EOD cases identified, Alzheimer’s disease (AD) was the most common subtype, making up 48.2% of cases, followed by behavioral variant frontotemporal dementia at 12.7%.
  • - The findings indicate that the incidence rates for EOD are higher than previous reports, with a notable increase in early-onset AD cases over time, while other EOD subtypes remained
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Background: Dementia is assumed to alter mental capacity, which may necessitate legal guardianship. However, only limited research exists on how dementia affects mental capacity, and most studies have focused solely on a medical perspective and concentrate on memory functions. The aim of this qualitative study was to investigate physicians' and legal experts' perceptions on a broad range of cognitive and neuropsychiatric domains potentially affecting mental capacity and the need for guardianship in people with dementia.

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