Aluminum dust exposure and risk of neurodegenerative diseases in a cohort of male miners in Ontario, Canada.

Objectives: We estimated associations between respirable aluminum exposure through McIntyre Powder (MP), a fine-sized aluminum and aluminum compound powder, and neurological disease in a retrospective cohort of mining workers from Ontario, Canada. Outcomes included Alzheimer's disease, Alzheimer's with other dementias, Parkinson's disease, parkinsonism, and motor neuron disease.

Methods: The cohort was created by linking a database of mining workers' work history to healthcare records.

Neurodegenerative diseases among miners in Ontario, Canada, using a linked cohort.

Objectives: We examined employment in mining occupations and industries and its association with neurological disease incidence in a linkage cohort from Ontario, Canada. Outcomes included Alzheimer's disease (alone and with other dementias), Parkinson's disease, parkinsonism, motor neuron disease and amyotrophic lateral sclerosis (ALS).

Methods: The Occupational Disease Surveillance System cohort was created by linking workers' compensation data and healthcare usage records.