Publications by authors named "Anne M Friemann"
J Atheroscler Thromb
January 2022
Article Synopsis
- The study investigates how thrombin activates factor XI (FXI) in the body, particularly how this process may be crucial for blood clotting and the development of thrombosis.
- Researchers analyzed patients receiving low-dose activated factor VII and those undergoing major orthopedic surgeries to measure levels of activated FXI (FXIa) and thrombin.
- Results show that FXIa levels increased significantly during surgery, indicating that local conditions at injury sites may be necessary for effective activation by thrombin.
