Publications by authors named "Anne Laure Mallet"
Background: Fecal incontinence is common in women with Crohn's disease, but little is known about the impact of childbirth, perianal Crohn's disease, and past surgical history on fecal incontinence.
Methods: Self-administered questionnaires were mailed to consecutive women referred to a tertiary gastroenterology centre with a focus on fecal incontinence and childbirth. These data were cross-referenced with a prospective database of the same patients' own Crohn's disease histories.
Background: Efficacy of azathioprine (AZA) in refractory ulcerative proctitis (UP) is unknown.
Methods: All patients treated with AZA for refractory UP in three referral centers between 2002 and 2012 were included. "Treatment success" in the long-term was defined as the absence of colectomy during follow-up, no need for anti-TNF during follow-up, no ongoing systemic steroids use, no adverse event leading to AZA withdrawal, and clinically quiescent disease at last follow-up.
Article Synopsis
- * Out of 1,994 high-resolution manometries, 44 patients with Jackhammer oesophagus were analyzed, revealing that 43.2% had GERD, while others either had no GERD or their status was undetermined.
- * Despite the high prevalence of GERD, significant improvement in swallowing difficulties (dysphagia) was observed in patients regardless of GERD status or the use of proton pump inhibitors, indicating that treatment outcomes may not rely heavily on these factors.
Background: The incidences of high-grade anal intraepithelial neoplasia (HSIL) and superficially invasive squamous cell carcinomas (SISCCA) related to human papillomavirus (HPV) have increased. These lesions can progress to invasive anal cancer. The aim of the study was to assess the clinical outcome with a special focus on the healing rate.
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