A national study of adverse effects and global quality of life among candidates for curative treatment for prostate cancer.

Objectives: To provide population-based estimates of typical adverse effects (AEs), e.g. urinary, bowel and sexual dysfunction, in patients with non-metastatic recurrence-free prostate cancer (PCa) by curative treatment method, including no treatment.

Fatigue in prostate cancer survivors treated with definitive radiotherapy and LHRH analogs.

Background: Few studies have dealt with chronic fatigue (CF) in definitive radiotherapy (RAD) patients during and after (neo-)adjuvant androgen deprivation therapy (ADT) for prostate cancer.

Methods: CF was the primary outcome in this population-based cross-sectional study as evaluated by the Fatigue Questionnaire. We compared the post-RAD levels of fatigue in two groups of > or = 1 year prostate cancer survivors; those with ongoing medical castration (HTcont) and those who had used a luteinizing hormone-releasing hormone analog (LHRHa), but had discontinued the therapy at the time of the survey (HTdis).

Initial management of prostate cancer: first year experience with the Norwegian National Prostate Cancer Registry.

Study Type: Therapy (individual cohort).

Level Of Evidence: 2b.

Objective: Improving a country's management of cancer patients requires continuous evaluation, and requires the availability of population-based prognostic and therapeutic variables.

Concordance between Gleason scores of needle biopsies and radical prostatectomy specimens: a population-based study.

Objective: To study the concordance between the Gleason scores of needle biopsies and radical prostatectomy (RP) specimens in a population-based registry, to clarify whether the concordance depends on the annual number of RP specimens assessed in the pathology unit, and to identify preoperative clinical factors that predict upgrading from a Gleason score of or=7 in the RP specimen.

Patients And Methods: Through the Cancer Registry of Norway, we identified 1116 patients with available Gleason scores from biopsy and RP specimens. Concordance was evaluated using the kappa coefficient, and predictors of concordance were assessed in univariate and multivariate logistic regression analyses.

[Curative treatment of prostatic cancer in Norway in 1998 and 2001].

Background: The two major therapeutic options for early diagnosed prostate cancer are radical prostatectomy or radiation therapy. The National Program for Prostate Cancer in Norway conducted this study in order to document the use of treatment with curative intention in five geographical regions in Norway.

Material And Methods: The study is based on data from the Cancer Registry of Norway on patients diagnosed with prostate cancer in 1998 and 2001.