Publications by authors named "Anne Kit-Hung Leung"
Article Synopsis
- Current severe COVID-19 treatments have side effects, and N-acetylcysteine (NAC) is being explored as a safer alternative, though research on its effectiveness in critical cases is limited.
- A study analyzed data from patients over 18 in ICU with respiratory failure and found that those receiving high-dose NAC (10 g/day) had higher 28-day mortality and fewer ventilator-free days compared to those who did not.
- After adjusting for variables, the matched analysis showed no significant impact of NAC on 28-day mortality rates or recovery metrics, suggesting it may not be an effective treatment for severe COVID-19 pneumonia.*
Purpose: Use of anticoagulation in patients on ECMO, especially in Chinese, has always been difficult. This study aimed to review the incidence of bleeding, thrombosis, and transfusion requirement in Chinese ECMO patients and to identify risk factors for bleeding complications.
Materials And Methods: This was a retrospective observational study of a tertiary hospital from 2010 to 2018.
Background: Intravenous fluid is important for resuscitation and maintenance of circuit flow in patients with extracorporeal membrane oxygenation, but fluid overload is widely recognized as detrimental in critically ill patients. This study aimed to evaluate the association between positive fluid balance and outcomes in adult patients treated with extracorporeal membrane oxygenation.
Methods: This was a retrospective observational study of a tertiary hospital from October 2010 to January 2018.
Speak-up culture in an intensive care unit in Hong Kong: a cross-sectional survey exploring the communication openness perceptions of Chinese doctors and nurses.
BMJ Open
August 2017
Objectives: Despite growing recognition of the importance of speaking up to protect patient safety in critical care, little research has been performed in this area in an intensive care unit (ICU) context. This study explored the communication openness perceptions of Chinese doctors and nurses and identified their perceptions of issues in ICU communication, their reasons for speaking up and the possible factors and strategies involved in promoting the practice of speaking up.
Design: A mixed-methods design with quantitative and sequential qualitative components was used.
Background. The emergence of a commercially prepared citrate solution has revolutionized the use of RCA in the intensive care unit (ICU). The aim of this study was to evaluate the safety profile of a commercially prepared citrate solution.
View Article and Find Full Text PDFObjective: To identify factors associated with the triage decision for patients classified as Society of Critical Care Medicine (SCCM) Triage Priority 3, and their outcomes.
Design: Single-centre, prospective, observational cohort study.
Setting: General intensive care unit in a tertiary regional hospital, over the 9 months January to September 2007.
Comparing the effectiveness of polyethylene covers (Gladwrap) with lanolin (Duratears) eye ointment to prevent corneal abrasions in critically ill patients: a randomized controlled study.
Int J Nurs Stud
November 2008
Background: In unconscious ventilated patients, various eye protective measures have been used to prevent corneal abrasions. Two randomized controlled studies in Australia had compared the effectiveness of polyethylene films and eye instillations to prevent corneal abrasions but results were inconsistent. The local acceptance of polyethylene films as a standard eye protective measure is still limited.
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