Accelerating the development of innovative cellular therapy products for the treatment of cancer.

The field of cell therapy is rapidly emerging as a priority area for oncology research and drug development. Currently, two chimeric antigen receptor T-cell therapies are approved by the US Food and Drug Administration and other agencies worldwide for two types of hematologic cancers. To facilitate the development of these therapies for patients with life-threatening cancers with limited or no therapeutic options, science- and risk-based approaches will be critical to mitigating and balancing any potential risk associated with either early clinical research or more flexible manufacturing paradigms.

Differentiating nursing leadership and management competencies.

As the foundation of evaluating content for nursing leadership and administration courses, leadership and management competencies were identified from a literature review of 140 articles published between 2000-2004. Similarities and differences among the competencies were assessed. A large intersection of common competencies was discovered, indicating a lack of discrimination between leadership and management competencies.

Preference for analgesic treatment for cancer pain among African Americans.

Over the past decade, there has been a surge of literature related to disparities in pain treatment between minority and non-minority patients. Conspicuously lacking from this body of literature is an effort to investigate the patient-level factors that might account for undertreatment of pain among minorities. The present qualitative descriptive study was designed to gain a preliminary understanding of the preference for analgesic treatment for cancer pain among African Americans and the factors shaping these preferences.

Factors associated with distress in urban residential fire survivors.

Purpose: To identify factors associated with recovery in a sample of urban residential fire survivors.

Design And Methods: 440 survivors, of residential fires were interviewed at approximately 3, 6, and 13 months after the fire to measure psychological distress. A set of factors was identified that correlated with survivors' ability to recover from the fire event.