Prognostic value of HMGA2, P16, and HPV in oral squamous cell carcinomas.

Purpose: Molecular markers are only occasionally used in diagnostics of oral squamous cell carcinoma (OSCC), even though they could influence decision making in individually designed cancer therapies. We analyzed the predictive value of the markers HPV, p16, and HMGA2 and the TNM classification in regard to survival and recurrence rates.

Material And Methods: A total of 91 OSCC cases were included in this study, with a follow up of up to 131 months.