Publications by authors named "Anne K Reed"

Article Synopsis
  • Nephrocalcinosis is a prevalent issue in farmed Atlantic salmon that affects their kidney function, but its effects on overall fish health are not fully understood.
  • A transcriptome study showed that salmon with severe nephrocalcinosis exhibited significant changes in gene expression, including reduced metabolism and energy production, along with increased activation of tissue repair and inflammatory responses.
  • These gene regulation changes, combined with tissue damage, could severely impact the survival of infected salmon.
View Article and Find Full Text PDF

The extent of cortical involvement of cerebral amyloid angiopathy (CAA)-related microbleeds (CMBs) remains unclear. We examined five consecutive patients with probable CAA and three non-demented elderly subjects with ultra-high field 7T MRI, to identify the precise location of CAA-related CMBs. In five CAA patients, 169 of a total of 170 lobar CMBs were located in cortical areas on 7T MRI, while a precise cortical versus juxtacortical localization was unable to be determined for 50/76 CMBs observed by conventional MRI.

View Article and Find Full Text PDF

Objective: To evaluate the local effect of small asymptomatic infarctions detected by diffusion-weighted imaging (DWI) on white matter microstructure using longitudinal structural and diffusion tensor imaging (DTI).

Methods: Nine acute to subacute DWI lesions were identified in 6 subjects with probable cerebral amyloid angiopathy who had undergone high-resolution MRI both before and after DWI lesion detection. Regions of interest (ROIs) corresponding to the site of the DWI lesion (lesion ROI) and corresponding site in the nonlesioned contralateral hemisphere (control ROI) were coregistered to the pre- and postlesional scans.

View Article and Find Full Text PDF