Publications by authors named "Anne Isabelle Lecuyer"
Background And Objective: Prostate cancer (PCa) was the leading incident cancer and 3rd leading cause of cancer death in men in France in 2015 with inter-regional disparities. The objectives were to describe PCa incidence and mortality in France and by region, using real life data from the National Health Data System and to identify the factors associated with all-cause or PCa-specific mortality.
Methods: Men aged ≥ 18years hospitalized and/or on long-term care for PCa (ICD-10 code C61) in France between 2010 and 2021 were included.
Article Synopsis
- * A total of 7,943 adult patients were identified, showing a prevalence of 10.4 cases per 100,000 and an annual incidence of 0.76 per 100,000, with complications such as hypertension, sleep apnea, and diabetes being commonly reported.
- * Findings indicate that diabetes significantly increases the risk for other serious health issues like myocardial infarction and cancer, emphasizing the need for comprehensive treatment approaches which include pituitary surgery and radiotherapy.
Background: It is unclear whether delays in care affect prognosis of patients with lung cancer. The primary objective of this study was to describe the care pathway of patients diagnosed with lung cancer in a French region. Secondary objectives were to identify markers associated with 1) time from imaging to treatment and 2) with 1-year survival.
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- Excessive waiting times for diagnostic imaging and treatment of pancreatic cancer patients can negatively affect their prognosis, but this impact varies based on timing and treatment options.
- A study analyzed the medical profiles of 324 patients in a French region, collecting data on key time intervals from initial visits to diagnosis and treatment commencement.
- Findings revealed that delays in receiving diagnostic imaging significantly correlated with a higher risk of death, especially for those with metastatic disease or who did not undergo tumor resection.
Background: Ursodeoxycholic acid (UDCA) therapy is commonly used in intrahepatic cholestasis of pregnancy (ICP).
Aim: To evaluate the efficacy and tolerance of UDCA in real-world conditions and to search for factors predictive of response to treatment.
Methods: This observational study included 98 consecutive patients suffering from pruritus during pregnancy associated with increased ALT levels or total bile acid (TBA) concentrations, without other causes of cholestasis.
Article Synopsis
- The study investigated the occurrence of ophthalmologic side effects, specifically retinal lesions and neurovisual impairment, in patients undergoing alpha-interferon therapy for viral hepatitis from 1995 to 2003.
- Out of 156 patients, 24% developed retinal lesions, such as cotton-wool spots and retinal hemorrhage, which were asymptomatic and resolved.
- Factors like a history of hypertension, age over 45, and the use of pegylated alpha-interferon were linked to an increased risk of retinopathy, while neurovisual impairment increased from 20% before treatment to 47% during treatment.