Frailty and pre-frailty associated with long-term diminished physical performance and quality of life in breast cancer and hematopoietic cell transplant survivors.

Physical frailty as a sign of accelerated aging is not well characterized in breast cancer (BC) and hematopoietic cell transplant (HCT) survivors and its correlation with outcomes and quality of life (QOL) is not defined. We conducted a prospective study to determine the prevalence of frailty in adult BC and HCT survivors, examine its impact on QOL, and determine its association with , a molecular biomarker for biological aging. The study included 59 BC and 65 HCT survivors.

Cardiac complications from cancer therapy.

In 2005, more than 10 million people in the United States were cancer survivors, and that number is expected to grow as therapies for cancer improve and the population ages. Although survival is something to be celebrated, it can be accompanied by a number of health problems secondary to the initial disease and its treatment. Cardiovascular problems are emerging as a particular concern among the survivor population.