Long-term mother and child mental health effects of a population-based infant sleep intervention: cluster-randomized, controlled trial.

Objectives: Maternal depression is an established risk for adverse child development. Two thirds of clinically significant depressive symptoms occur in mothers reporting an infant sleep problem. We aimed to determine the long-term effects of a behavioral intervention for infant sleep problems on maternal depression and parenting style, as well as on child mental health and sleep, when the children reached 2 years of age.

The Light Time-Use Diary and preschool activity patterns: exploratory study.

Aim: To conduct an exploratory study of time-use patterns in Australian 5-year-old children, and to pilot the novel Children's Light Time-Use Diary as a potential tool for investigating relationships between children's time-use and weight status.

Methods: Subjects for the present cross-sectional study were drawn from an established longitudinal cohort and included eighty-four 5-year-old Australian children (36 males) originally recruited as infants in three local government areas of Melbourne. Children were weighed and measured, and body mass index (BMI; kg/m(2)) calculated.

Sleep problems in young infants and maternal mental and physical health.

Aim: Sleep problems in the second 6 months of life are common and associated with maternal depression. This paper extends previous research to (i) establish the prevalence of sleep problems in younger infants from a broader socio-economic spectrum, (ii) examine the relationship between infant sleep problems and maternal physical, as well as mental, health, and (iii) explore mothers' sleep quality as a potential mediator of this relationship.

Design: Cross-sectional, community survey in Melbourne, Australia.

Improving infant sleep and maternal mental health: a cluster randomised trial.

Objectives: To determine whether a community-delivered intervention targeting infant sleep problems improves infant sleep and maternal well-being and to report the costs of this approach to the healthcare system.

Design: Cluster randomised trial.

Setting: 49 Maternal and Child Health (MCH) centres (clusters) in Melbourne, Australia.

Maternal concern and perceptions of overweight in Australian preschool-aged children.

Objective: To assess maternal concern about overweight in Australian preschool-aged children and factors predicting maternal concern about children's current and future weight status.

Design: Cross-sectional survey of child's body mass index and parent questionnaire.

Setting: Metropolitan Melbourne, Victoria, 2002.

Endometrial expression of calbindin (CaBP)-d28k but not CaBP-d9k in primates implies evolutionary changes and functional redundancy of calbindins at implantation.

The endometrium is hostile to embryo implantation except during the 'window of receptivity'. A change in endometrial gene expression is required for the development of receptivity. Calbindin-d9k (CaBP-d9k) and calbindin-d28k (CaBP-d28k) are proteins possessing EF-hand motifs which have high affinity for Ca2+ ions.

Identification and cloning of two isoforms of human high-temperature requirement factor A3 (HtrA3), characterization of its genomic structure and comparison of its tissue distribution with HtrA1 and HtrA2.

In the present study, we identified an additional member of the human high-temperature requirement factor A (HtrA) protein family, called pregnancy-related serine protease or HtrA3, which was most highly expressed in the heart and placenta. We cloned the full-length sequences of two forms (long and short) of human HtrA3 mRNA, located the gene on chromosome 4p16.1, determined its genomic structure and revealed how the two mRNA variants are produced through alternative splicing.