Publications by authors named "Anne Christine Wiuff"
Article Synopsis
- Antipsychotic polypharmacy, or the use of multiple antipsychotic medications, is common in clinical practice, but it carries a higher risk of side effects and there's little proof that it works better than using a single medication.
- A systematic review analyzed 517 studies involving over 4.4 million individuals to determine the prevalence and trends of antipsychotic polypharmacy across different mental disorders.
- The findings revealed that 24.8% of individuals were using multiple antipsychotics, with higher rates in those with schizophrenia spectrum disorders and significant regional variations, showing an overall trend of increasing polypharmacy from 1970 to 2023.
Article Synopsis
- The study investigates the long-term effects of lithium treatment on renal and endocrine systems in patients with bipolar disorder, addressing limitations of previous research with selected populations and short follow-ups.
- Researchers analyzed data from both lithium users and matched reference patients, focusing on diagnoses of renal, thyroid, and parathyroid diseases, as well as biochemical marker levels over time.
- Results indicated that while lithium users showed some adverse trends in biochemical markers and increased rates of certain diseases, the occurrence of severe outcomes was low, suggesting that significant adverse effects during long-term treatment may be rare.
Background: Patients suffering from Chronic Spontaneous Urticaria (CSU) may be recalcitrant to treatment with high dose second-generation antihistamines. These patients are, according to international guidelines, eligible to treatment with omalizumab. Treatment with omalizumab has proven to be very effective for this group of patients.
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