Publications by authors named "Anne Caudron"
Discoidin domain receptors: A promising target in melanoma.
Pigment Cell Melanoma Res
September 2019
Article Synopsis
- The study investigates the role of discoidin domain receptor 1 (DDR1) in human melanoma, noting its high expression in melanoma cases and its link to worse patient outcomes.
- High DDR1 levels are associated with specific clinical factors like Clark level, ulceration, and BRAF mutations in melanoma patients.
- Reducing DDR1 expression through techniques like siRNA inhibited melanoma cell growth and movement, while a DDR1 inhibitor showed promise in decreasing melanoma cell proliferation in lab settings and tumor models.
CD147 has been implicated in melanoma invasion and metastasis mainly through increasing metalloproteinase synthesis and regulating VEGF/VEGFR signalling. In this study, the prognostic value of CD147 expression was investigated in a cohort of 196 cutaneous melanomas including 136 consecutive primary malignant melanomas, 30 lymph nodes, 16 in-transit and 14 visceral metastases. A series of 10 normal skin, 10 blue nevi and 10 dermal nevi was used as control.
View Article and Find Full Text PDFImproving Multi-Disciplinary Meetings (MDM) is one of the 70 clauses of the French Cancer Plan of 2003-2007. The French High Authority of Health (HAS) and the National Cancer Institute (INCa) have established guidelines to standardize MDM concerning cancer care. No objective assessment of cutaneous cancer (dermato-oncology) MDM has been published yet, despite the growing numbers in the incidence of skin cancers.
View Article and Find Full Text PDFIntroduction: A combination of disk space narrowing and vacuum phenomenon on radiographs of the spine is usually considered a reliable indicator of degenerative disk disease. We report a case in which vacuum phenomenon was related to Clostridium perfringens discitis.
Methods: A 79-year-old woman was admitted for inflammatory low back pain that had worsened steadily over the last 2 months.