Decrease in serum procalcitonin levels over time during treatment of acute bacterial meningitis.

Introduction: The aim of this study was to describe the change in serum procalcitonin levels during treatment for community-acquired acute bacterial meningitis.

Methods: Out of 50 consecutive patients presenting with bacterial meningitis and infection at no other site, and who had received no prior antibiotic treatment, 48 had a serum procalcitonin level above 0.5 ng/ml on admission and were enrolled in the study.