Publications by authors named "Anne C Houtman"

Article Synopsis
  • This feasibility study examined collecting and analyzing tear proteins from preterm infants to understand the potential links to retinopathy of prematurity (ROP) and to find possible prognostic markers.
  • Using Schirmer's test and mass spectrometry, researchers collected tear samples from 12 infants scheduled for ROP screening, identifying 701 proteins, including key markers associated with ROP risk.
  • The findings suggest that tear sampling is practical, indicating a need for a larger study to explore its role in identifying ROP and improving understanding of retinal development.
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Background/objectives: Screening for retinopathy of prematurity (ROP) is a core healthcare intervention in premature babies to avoid preventable sight loss. A variety of screening criteria are in place globally for this purpose. The Royal College of Paediatrics and Child Health recently updated the United Kingdom ROP screening guidelines (March 2022).

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Background: Patients with hereditary tumor syndromes undergo periodical magnetic resonance imaging (MRI) screening with Gadolinium contrast. Gadolinium accumulation has recently been described in the central nervous system after repeated administrations. The prevalence and rate of accumulation in different subgroups of patients are unknown.

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Purpose: Besides chiasmal hemidecussation, interhemispheric connections are likely important in human binocularity. The corpus callosum (CC) is the major fiber bundle in the mammalian brain which mostly connects homologous cortical areas in the two hemispheres. Visual interhemispheric connections were found abnormal in strabismic cats.

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In humans, images in the median plane of the head either fall on both nasal hemi-retinas or on both temporal hemi-retinas. Interhemispheric connections allow cortical cells to have receptive fields on opposite sides. The major interhemispheric connection, the corpus callosum, is implicated in central stereopsis and disparity detection in front of the fixation plane.

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