Publications by authors named "Anne C Boehmer"
Resequencing of VAX1 in patients with nonsyndromic cleft lip with or without cleft palate.
Birth Defects Res A Clin Mol Teratol
November 2012
Article Synopsis
- - Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is common and arises from both genetic and environmental factors, with the VAX1 gene at chromosome 10q25.3 being a strong candidate linked to these conditions.
- - In a study involving genetic sequencing of 384 NSCL/P patients and 384 controls, researchers found 18 genetic variations in the VAX1 gene, 15 of which were rare and newly reported; however, the association with NSCL/P was not statistically significant.
- - The findings suggest that rare variants in VAX1 do not strongly cause NSCL/P, indicating the need for further investigation into the gene's function to clarify its potential role in cran