Publications by authors named "Anne Bouvard"
Article Synopsis
- Current guidelines for chronic lymphocytic leukemia (CLL) recommend checking the IGHV gene mutation status before starting treatment, but traditional NGS methods face limitations in cost and technical requirements.
- The new Next-CLL method allows for IGHV mutation analysis using standard NGS devices, streamlining the process in routine labs and demonstrating higher reliability compared to traditional Sanger sequencing.
- Validation of Next-CLL showed perfect concordance with reference techniques and no significant bias in IGHV usage, making it a practical and effective tool for evaluating prognosis and treatment options for CLL patients.
