Publications by authors named "Anne Bastholm Blicher"
Artificial indoor lighting can disturb sleep and increase depressive symptoms; both common complaints in psychiatric inpatients. In this trial we aimed to improve sleep in psychiatric inpatients using a circadian lighting environment. Investigator-blinded parallel-group randomised controlled effectiveness trial in an inpatient psychiatric ward with adjustable lighting.
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- The study investigates the role of the neurotransmitter GABA in major depression and its relationship with electroconvulsive therapy (ECT) through magnetic resonance spectroscopy.
- Both patients with major depression and healthy subjects were analyzed, revealing no significant differences in GABA levels between the groups prior to treatment.
- Post-ECT, patients showed improvement in depression scores, but only a notable decrease in another metabolite, N-acetylaspartate (NAA), was observed, suggesting potential neuronal loss or dysfunction rather than changes in GABA levels.