Publications by authors named "Anne B Blicher"
Background: The six-item version of the Positive and Negative Syndrome Scale (PANSS-6) has shown promise as a brief measure of the severity of core symptoms of schizophrenia. However, since all prior analyses of the PANSS-6 were based on data extracted from studies using the full 30-item PANSS (PANSS-30), it remains unknown whether it is possible to obtain valid information for the PANSS-6 ratings via a brief interview, such as the Simplified Negative and Positive Symptoms Interview (SNAPSI).
Aims: We aimed to validate the PANSS-6 ratings obtained via the SNAPSI using the PANSS-6 scores extracted from the PANSS-30 ratings obtained via the comprehensive Structured Clinical Interview for PANSS (SCI-PANSS) as the gold-standard reference.
Artificial indoor lighting can disturb sleep and increase depressive symptoms; both common complaints in psychiatric inpatients. In this trial we aimed to improve sleep in psychiatric inpatients using a circadian lighting environment. Investigator-blinded parallel-group randomised controlled effectiveness trial in an inpatient psychiatric ward with adjustable lighting.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the role of the neurotransmitter GABA in major depression and its relationship with electroconvulsive therapy (ECT) through magnetic resonance spectroscopy.
- Both patients with major depression and healthy subjects were analyzed, revealing no significant differences in GABA levels between the groups prior to treatment.
- Post-ECT, patients showed improvement in depression scores, but only a notable decrease in another metabolite, N-acetylaspartate (NAA), was observed, suggesting potential neuronal loss or dysfunction rather than changes in GABA levels.
Purpose: The six-item version of the Positive And Negative Syndrome Scale (PANSS-6) is a brief rating scale focusing on core symptoms of schizophrenia. In order to facilitate rating of PANSS-6 and selected items from other common psychiatric rating scales, we recently developed the Simplified Negative and Positive Symptoms Interview (SNAPSI). The objective of the present study was to test the inter-rater reliability of PANSS-6 ratings obtained using the SNAPSI.
View Article and Find Full Text PDF