Motor Activity in Aging: An Integrated Approach for Better Quality of Life.

Old age is normally associated with stereotypical structural and physiological changes in the brain that are caused by deterioration in elementary cognitive, sensory, and sensorimotor functions as well as increased susceptibility to stress. These changes are connected with gait impairment and falls, especially among patients with common neurological diseases. Even in the absence of history of falling or when there is no physical injury after a fall, many older people develop a fear of falling that leads to restricted mobility, reduced activity, depression, social isolation, worsened metabolic disease, and increasing risk of cardiovascular morbidity and mortality.

Automatic correction of intensity inhomogeneities improves unsupervised assessment of abdominal fat by MRI.

Purpose: To demonstrate that unsupervised assessment of abdominal adipose tissue distribution by magnetic resonance imaging (MRI) can be improved by integrating automatic correction of signal inhomogeneities.

Materials And Methods: Twenty subjects (body mass index [BMI] 23.7-44.

Muscle metabolism and exercise tolerance in subclinical hypothyroidism: a controlled trial of levothyroxine.

Background: Neuromuscular symptoms and impaired muscle energy metabolism have been described in subclinical hypothyroidism (sHT).

Aim: The aim of the study was to evaluate the energy and substrate response to exercise in sHT patients using a standardized protocol and to test the effect of L-T(4) replacement in a double-blind, randomized, placebo-controlled fashion.

Patients And Methods: We studied 23 sHT patients and 10 matched euthyroid controls.