Publications by authors named "Annalisa Merlo"
In the staging of cancer patients, transient and spontaneously reversible bilateral adrenal hypertrophy may mimic a secondary localization of the disease. We discuss the case of an 82-year-old male patient with suspected testicular neoplasia in which abdominal CT examination reveals the onset of a bilateral macronodular adrenal enlargement, suggesting the diagnostic hypothesis of primary testicular neoplasia with secondary adrenal localization. The subsequent FDG-PET/CT study showed hyper-metabolism of the testicular mass, while the adrenal glands, surprisingly, did not show increased uptake of the radiotracer.
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- The study evaluated the effectiveness of contrast-enhanced CT (CECT) compared to unenhanced CT (UECT) in staging and assessing treatment response for F-FDG-avid lymphomas using a 64-slice PET/CT scanner.
- While CECT identified a few additional lesions and had some agreement with PET results, the overall added diagnostic value was below the clinically significant threshold, with no significant difference in accuracy between UECT and CECT.
- The findings suggest that CECT may not be necessary for staging and treatment assessment of F-FDG-avid lymphomas, potentially reducing radiation exposure and risks associated with contrast use.