Warfarin inhibits vitamin-K dependent proteins involved in bone mineralization and the prevention of vascular calcification (bone Gla protein BGP, matrix Gla protein MGP). In this multicenter, cross-sectional study with 3-year follow-up, data from 387 patients on hemodialysis for ≥1 year at 18 dialysis units were analyzed. Patients on warfarin treatment for > 1 year (11.
View Article and Find Full Text PDFUltrasonography is a non-invasive,well-controlled, quickly and easily available diagnostic procedure for the patient, is repeatable and not using ionizing radiation. For all these features plays an important role in the clinical management of patients undergoing dialysis. A census of the National Renal Ultrasound Study Group from Italian Society of Nephrology revealed that the 73.
View Article and Find Full Text PDFBackground: The imbalance between synthesis and degradation of mesangial matrix causes glomerulosclerosis and leads to renal failure. Hepatocyte growth factor (HGF) has been shown to reduce the progression in murine models of chronic renal failure. The present study evaluated the effect of HGF on the extracellular matrix turnover and on c-met receptor in human glomeruli.
View Article and Find Full Text PDF