Publications by authors named "Annaelle V Zietz"
Atherosclerosis
November 2022
Article Synopsis
- The study investigates whether genetically lower PCSK9 levels can reduce lipoprotein(a) (Lp(a)) and its impact on cardiovascular diseases like coronary artery disease (CAD) and ischemic stroke (IS).
- Using UK Biobank data with over 310,000 individuals, researchers found that PCSK9 inhibition was linked to a significant decrease in Lp(a) levels and a slight reduction in the risk of CAD and IS.
- While there is an association between PCSK9 inhibition and lowered Lp(a), the reduction in Lp(a) accounts for only a small portion of the overall decrease in risk for CAD and IS.
